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The appropriate response to that uncertainty is not to abandon the compound but to use it within a structured clinical framework: defined goals, evidence-appropriate dosing, quality-assured sources, systematic monitoring, and ongoing reassessment as the science matures

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In their announcement about the retatrutide study, Eli Lilly medical experts said that about 11% of study volunteers who received the highest dose of the drug stopped taking it and dropped out of the study due to unpleasant side effects